Changes in GnRH pulse frequency in females is controlled by circulating levels of
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GnRH is secreted by the hypothalamus which stimulates the anterior lobe of pituitary gland to secrete luteinising hormone (LH) and follicle stimulating hormone (FSH). FSH stimulates the growth of the ovarian follicles and stimulates the formation of estrogens. LH stimulates the corpus luteum to secrete progesterone. Rising levels of progesterone and estrogen inhibits the release of GnRH , which in turn, inhibits the production of FSH and LH.
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